T-2 Toxin EIA

Cat. No.: 5121TOXp

 

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T-2 toxin is one of a family of closely related compounds produced by several Fusarium species. These compounds are derivatives of a ring system referred to as trichothecenes. There are more than 20 naturally occurring compounds produced by Fusarium species which contain similar structures, including diacetoxyscirpenal, nivalenol, diacetylnivalenol, deoxynivalenol (DON), HT-2 toxin and fusaron X. T-2 toxins and related compounds have been implicated with a disease known as mouldy corn toxicosis of swine, symptoms of which include refusal to eat, lack of weight gain, digestive disorders and diarrhea, ultimately leading to death. T-2 toxin is quite toxic to rats, trout and calves with oral LD50 values of 3.8, 6.1 and 0.6 mg/kg, respectively. T-2 toxin is also thought to be one of the toxins involved in the human disease alimentary toxic aleukia and stachybotryotoxicoses of horses. T-2 toxin is not thought to be carcinogenic. T-2 toxins are often detected in cereal grains, mainly corn and wheat, and in feed. In Europe no Maximum Levels are established legally. In the T-2 toxin EIA-kit of Euro-Diagnostica an antiserum is used that cross-reacts with T-2 toxin (100%) and acetyl-T-2 toxin (12.7%). The limit of detection for T-2 toxin was found to be 50 µg/kg (ppb).